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KMID : 0882420070730050503
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Korean Journal of Medicine
2007 Volume.73 No. 5 p.503 ~ p.511
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The prevalence of microalbuminuria and associated factors in newly diagnosed thpe 2 diabetes mellitus in Korea
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Kim Dong-Jin
Ryu Seong-Jin
Seo Young-Jin
Kim Nam-Hoon
Chung Hye-Soo
Eun Chai-Ryoung
Choi Hey-Jung
Kim Hye-Sook
Yang Sae-Jeong
Park Ju-Ri
Yoo Hye-Jin
Park Soo-Yeon
Lee Yun-Jeong
Ryu Ohk-Hyun
Lee Kye-Won
Kim Hee-Young
Seo Ji-A
Kim Sin-Gon
Kim Nan-Hee
Choi Kyung-Mook
Baik Sei-Hyun
Choi Dong-Seop
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Abstract
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Background : To determine the prevalence and the associated factors of microalbuminuria in Korean subjects with newly diagnosed type 2 diabetes mellitus.
Methods : A total of 304 patients with newly diagnosed type 2 diabetes mellitus that visited Anam Hospital, Korea University Medical Center, were studied cross-sectionally for the presence of microalbuminuria and other micro- and macrovascular complications. Microalbuminuria was calculated by the amount of albumin excretion in the urine for 24 hrs (30-299 mg/24hr) or by the albumin creatinine ratio in a spot urine sample (30-299 mg/g creatinine). Subjects were divided into two groups: the normoalbuminuria group and the microalbuminuria group.
Results : The prevalence of microalbuminuria, normoalbuminuria and overt proteinuria in patients with newly diagnosed type 2 diabetes mellitus was 17.1%, 80.3% and 2.6%. respectively. Microalbuminuria was significantly correlated with the body mass index (BMI), fasting insulin level, fasting C-peptide level and triglyceride level. The number of metabolic syndrome components was significantly correlated with the amount of microalbuminuria. In patients with microalbuminuria and without retinopathy, the correlation of microalbuminuria and the presence of metabolic syndrome was also significant.
Conclusion : The prevalence of microalbuminuria in 304 Korean patients with newly diagnosed type 2 diabetes mellitus was 17.1%, and microalbuminuria had a correlation with the BMI, fasting insulin level, fasting C-peptide level, HOMA level, triglyceride level and the presence of metabolic syndrome.
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KEYWORD
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Microalbuminuria, Prevalence, Diabetes mellitus , type 2, Metabolic syndrome
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